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Clinical trials for Total Knee Arthroplasty

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    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    81 result(s) found for: Total Knee Arthroplasty. Displaying page 1 of 5.
    1  2  3  4  5  Next»
    EudraCT Number: 2009-012043-42 Sponsor Protocol Number: RSCH 01/10 Start Date*: 2011-07-11
    Sponsor Name:Royal Surrey County Hospital NHS Trust
    Full Title: The Effect of a Human Surgical Sealant on Range of Motion in Total Knee Replacement
    Medical condition: Use of human surgical sealant during total knee replacement and if this affects knee movement for the 1st year after surgery.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10057129 Revision of total knee arthroplasty LLT
    13.1 10042613 - Surgical and medical procedures 10044094 Total knee replacement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-002635-23 Sponsor Protocol Number: NBF_HK_02_2018. Start Date*: 2018-10-23
    Sponsor Name:Anaesthesia Department, Hvidovre Hospital, Capital Region of Denmark.
    Full Title: Highdose steroids in High Pain Responders undergoing total knee-arthroplasty - A randomized doubleblindet controlled trial.
    Medical condition: Perioperative management of a group of High Pain Responders in total knee-arthroplasty because of kneeosteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    20.0 10042613 - Surgical and medical procedures 10003398 Arthroplasty of knee LLT
    20.1 100000004863 10054711 Postoperative pain LLT
    20.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-002170-39 Sponsor Protocol Number: Knemo01 Start Date*: 2017-09-14
    Sponsor Name:Eksote
    Full Title: Combination of intrathecal morphine and local infiltration analgesia in treatment postoperative pain of total knee arthroplasty
    Medical condition: Postoperative pain after total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000021309 10003398 Arthroplasty of knee LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003169-33 Sponsor Protocol Number: 2013-578 Start Date*: 2013-10-30
    Sponsor Name:Anders Troelsen
    Full Title: Evaluation of intra articular Tranexamic acid for reduction of total blood loss in total knee unilateral arthroplasty
    Medical condition: The benefit of additional Tranexamic Acid (TXA) injected intra-articular at the end of surgery for patients undergoing a unilateral total knee arthroplasty in addition to conventional IV TXA to red...
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10003398 Arthroplasty of knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-003756-37 Sponsor Protocol Number: ANT-005 Start Date*: 2020-02-25
    Sponsor Name:Anthos Therapeutics
    Full Title: A Multicenter, Randomized, Open-Label, Blinded Endpoint Evaluation, Active-Controlled, Dose-Ranging Study to Compare the Efficacy and Safety of i.v. MAA868 and s.c. Enoxaparin in Adult Patients Und...
    Medical condition: Elective unilateral total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) BE (Completed) LV (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2015-001214-10 Sponsor Protocol Number: AAUH-01-2015 Start Date*: 2015-06-02
    Sponsor Name:Aalborg universitets hospital [...]
    1. Aalborg universitets hospital
    2. Ortopædkirurgisk forskningsenhed, Aalborg universitetshospital
    Full Title: Analgetic effect of perioperative klorzoxazon at total hip or knee arthroplasty
    Medical condition: Perioperative pain after incertion of hip or knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    18.0 10042613 - Surgical and medical procedures 10020096 Hip arthroplasty PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-003051-37 Sponsor Protocol Number: 2013-07-03 Start Date*: 2013-08-28
    Sponsor Name:Kuopion yliopistollinen sairaala
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    16.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    16.0 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000126-39 Sponsor Protocol Number: 07-127 Start Date*: 2008-05-26
    Sponsor Name:CHU de Caen
    Full Title: Analgésie post-opératoire pour prothèse totale de genou par cathéter péri-nerveux fémoral: Etude comparative de la levobupivacaine 0,125% versus ropivacaine 0, 2%. Protocole LPTG
    Medical condition: Prothèse totale du genou
    Disease: Version SOC Term Classification Code Term Level
    9.1 10044094 Total knee replacement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001099-39 Sponsor Protocol Number: SM1-KAKG-2018 Start Date*: 2018-06-08
    Sponsor Name:Naestved Hospital
    Full Title: Dexamethasone twice for pain treatment of total knee arthroplasty (DEX-2-TKA) A randomized blinded placebo-controlled clinical trial
    Medical condition: Postoperative pain after total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-006110-20 Sponsor Protocol Number: RepeatDoseTKAHPR2020 Start Date*: 2021-06-18
    Sponsor Name:Vejle Sygehus, Ortopædkirurgisk afdeling, Forskningsenheden (COFU)
    Full Title: Repeat dose steroid to prevent pain relapse after Total Knee Arthroplasty in patients with high pain response - A randomized blinded placebo-controlled trial
    Medical condition: Periooperative management of total knee-arthroplasty because of knee-osteoarthritis.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006930-17 Sponsor Protocol Number: 01/2006 Start Date*: 2007-03-20
    Sponsor Name:HOSPITAL GENERAL DE VIC
    Full Title: ANESTESIA SUBARACNOIDEA SELECTIVA. COMPARACIÓN DE BUPIVACAINA HIPERBÁRICA CON PRILOCAINA HIPERBÁRICA PARA ARTROSCOPIA DE RODILLA O HERNIOPLASTIA INGUINAL EN CIRUGIA MAYOR AMBULATORIA
    Medical condition: Pacientes que se sometan a una artroplastia de rodilla ya sea diagnóstica o terapéutica y pacientes que se sometan a una hernioplastia inguinal
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023469 Knee arthroplasty LLT
    9.1 10022025 Inguinal herniorrhaphy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-018245-21 Sponsor Protocol Number: H-A-2009-069 Start Date*: 2010-06-22
    Sponsor Name:Rigshospitalet
    Full Title: Fibrinklæber ved bilateral knæalloplastik – et prospektivt randomiseret studie med fokus på: blodtab, smerte, ROM, hævelse og styrke
    Medical condition: Formålet med nærværende studie er at undersøge om – og i bekræftende fald omfanget heraf – fibrinklæber (Evicel) reducerer blødningen efter Total Knæ Alloplastik (kunstigt knæ)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10044094 Total knee replacement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000692-14 Sponsor Protocol Number: HKO-22112010 Start Date*: 2011-11-03
    Sponsor Name:Hannu Kokki
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10067624 Knee arthritis LLT
    14.0 10022117 - Injury, poisoning and procedural complications 10036284 Post-operative hip pain LLT
    14.0 10042613 - Surgical and medical procedures 10023479 Knee total replacement LLT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10065955 Hip arthrosis LLT
    14.0 10042613 - Surgical and medical procedures 10003397 Arthroplasty of hip LLT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10031174 Osteoarthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-005180-40 Sponsor Protocol Number: Protocol_PPB_TKA_31122017 Start Date*: 2018-02-19
    Sponsor Name:Aarhus University Hospital
    Full Title: The effect of the popliteal plexus block on postoperative pain after total knee arthroplasty - a randomized, controlled, double-blinded study
    Medical condition: Postoperative posterior pain after total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    20.0 10042613 - Surgical and medical procedures 10002325 Anesthesia local LLT
    20.0 10042613 - Surgical and medical procedures 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002136-15 Sponsor Protocol Number: 2008 AN02 Start Date*: 2010-01-25
    Sponsor Name:Ninewells Hospital and Medical School
    Full Title: A randomised single blind study comparing the molar ED50 of levobupivacaine and molar ED50 of ropivacaine when administered as a femoral perineural infusion for pain relief after total knee replace...
    Medical condition: Pain after total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003398 Arthroplasty of knee LLT
    9.1 10036236 Postoperative pain relief LLT
    9.1 10024758 Local anaesthesia LLT
    9.1 10041536 Spinal anaesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024115-14 Sponsor Protocol Number: 05-AnIt-09/UKM10_0027 Start Date*: 2011-04-29
    Sponsor Name:University Hospital Muenster
    Full Title: Preoperative Intravenous Ferric Carboxymaltose (Ferinject) in Patients with Orthopaedic Surgery and High Risk of Blood Loss
    Medical condition: Patients with iron deficiency anemia scheduled to undergo orthopedic surgery with high risk of bleeding
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10058829 Elective surgery PT
    14.1 10042613 - Surgical and medical procedures 10044088 Total hip replacement LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10005127 Bleeding postoperative LLT
    14.1 10005329 - Blood and lymphatic system disorders 10066573 Chronic iron deficiency anemia LLT
    14.1 10042613 - Surgical and medical procedures 10057129 Revision of total knee arthroplasty LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10051536 Intraoperative bleeding LLT
    14.1 10005329 - Blood and lymphatic system disorders 10022975 Iron deficiency anemia secondary to blood loss (chronic) LLT
    14.1 10042613 - Surgical and medical procedures 10069749 Internal fixation of spine PT
    14.1 10022117 - Injury, poisoning and procedural complications 10051386 Wound bleeding LLT
    14.1 10042613 - Surgical and medical procedures 10020096 Hip arthroplasty PT
    14.1 10005329 - Blood and lymphatic system disorders 10022976 Iron deficiency anemia secondary to inadequate dietary iron intake LLT
    14.1 10042613 - Surgical and medical procedures 10051060 Hip surgery PT
    14.1 10042613 - Surgical and medical procedures 10039727 Scoliosis surgery PT
    14.1 10042613 - Surgical and medical procedures 10049130 Back surgery LLT
    14.1 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    14.1 10005329 - Blood and lymphatic system disorders 10022977 Iron deficiency anemia, unspecified LLT
    14.1 10042613 - Surgical and medical procedures 10020102 Hip replacement LLT
    14.1 10042613 - Surgical and medical procedures 10057128 Revision of hip arthroplasty LLT
    14.1 10042613 - Surgical and medical procedures 10044094 Total knee replacement LLT
    14.1 10042613 - Surgical and medical procedures 10049662 Knee surgery NOS LLT
    14.1 10005329 - Blood and lymphatic system disorders 10022974 Iron deficiency anemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-003795-39 Sponsor Protocol Number: TKADEX Start Date*: 2020-12-15
    Sponsor Name:Turku University Hospital
    Full Title: Premedication with intranasal dexmedetomidine in sedation of patients undergoing total knee arthroplasty (TKADEX) - a prospective, double blinded randomized controlled trial
    Medical condition: Knee arthrosis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002704-41 Sponsor Protocol Number: SM2-UG12 Start Date*: 2012-09-18
    Sponsor Name:Rigshospitalet
    Full Title: Effect of Adductor-Canal-Blockade on postoperative pain, ability to walk and morphine consumption after total knee arthroplasty: A randomised study
    Medical condition: Treatment of postoperative pain in patients after total knee arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002634-20 Sponsor Protocol Number: NBF_HK_01_2018 Start Date*: 2018-10-23
    Sponsor Name:Anaesthesia Department, Hvidovre Hospital, Capital Region of Denmark
    Full Title: Highdose steroid for total knee arthroplasty - A randomized doubleblindet controlled trial.
    Medical condition: Perioperative management of total knee-arthroplasty because of knee-osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-001229-27 Sponsor Protocol Number: Fybex02/Parexel 71786 Start Date*: 2005-11-23
    Sponsor Name:Bio Products Laboratory
    Full Title: A randomized, sigle-blind, parallel group, multicentre comparative study to assess the efficacy and safety of an application of Fybex (fibrin sealant) to the operative field, for the reduction of p...
    Medical condition: Total knee arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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